Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31518263 | 0.83 | MEN1 (0.78) | MEN1KMT2ACDC7PIM1CSNK2B | |
| SCHEMBL3328962 | 0.83 | MEN1 (1.00) | MEN1KMT2APDCD1LG2CD274CDC7 | |
| SCHEMBL21465760 | 0.81 | MEN1 (0.50) | MEN1KMT2AHTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL31738166 | 0.81 | MEN1 (0.65) | MEN1KMT2APDCD1LG2CD274CDC7 | |
| SCHEMBL30888638 | 0.80 | PTGDR2 (0.45) | MEN1KMT2AHTR2CPTGDR2HTR2A | |
| SCHEMBL28521137 | 0.80 | MEN1 (0.48) | MEN1KMT2AHTR2C | |
| SCHEMBL16559758 | 0.79 | MEN1 (0.63) | MEN1KMT2APDCD1LG2CD274CDC7 | |
| SCHEMBL31518202 | 0.78 | MEN1 (0.62) | MEN1KMT2APDCD1LG2CD274CDC7 | |
| SCHEMBL21516972 | 0.78 | MEN1 (0.69) | MEN1KMT2AHTR2CPTGDR2HTR2A | |
| SCHEMBL21491464 | 0.78 | MEN1 (0.89) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683029-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117430601-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112437772-B | Bcl-2 inhibitors | 百济神州有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | disclosed |