Methylene Chloride

Methylene Chloride

SCHEMBL28533175

CCCCCCl.CCN1CCNC(=O)C1=O.ClCCl

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
FAAH O00519 1/20 0.37
NAAA Q02083 1/20 0.37
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35
POLB P06746 1/20 0.30
PLA2G2A P14555 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27866702 0.98 MEN1 (0.39) MEN1KMT2AFAAHNAAAALDH1A1
SCHEMBL1277501 0.83 MEN1 (0.37) MEN1KMT2AFAAHNAAAALDH1A1
Hydrochloric Acid SCHEMBL28569637 0.82 MEN1 (0.36) MEN1KMT2AFAAHNAAAALDH1A1
SCHEMBL28919237 0.79 POLB (0.34) MEN1KMT2AALDH1A1POLB
SCHEMBL10384849 0.79 GAA (0.36) MEN1KMT2AFAAHNAAAALDH1A1
SCHEMBL11188690 0.79 MEN1 (0.51) MEN1KMT2AFAAHNAAAALDH1A1
Piperazine SCHEMBL27495864 0.79 MEN1 (0.34) MEN1KMT2AFAAHNAAAALDH1A1
SCHEMBL28533173 0.78 MEN1 (0.36) MEN1KMT2AFAAHNAAA
SCHEMBL11047867 0.78 MEN1 (0.50) MEN1KMT2AFAAHNAAAALDH1A1
SCHEMBL832433 0.77 MEN1 (0.58) MEN1KMT2AFAAHNAAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112321605-B Preparation method of piperacillin 山东安信制药有限公司 2022-01-28 CN disclosed
CN-112321605-A Preparation method of piperacillin 山东安信制药有限公司 2021-02-05 CN disclosed