SCHEMBL28533335

SCHEMBL28533335

C=C(C(C)=O)C(=O)OC=Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HDAC3 O15379 3/20 0.40
HDAC4 P56524 3/20 0.40
HDAC1 Q13547 3/20 0.40
HDAC2 Q92769 3/20 0.40
HDAC8 Q9BY41 3/20 0.40
HDAC6 Q9UBN7 3/20 0.40
ALDH1A1 P00352 3/20 0.40
RECQL P46063 3/20 0.40
MAPT P10636 3/20 0.40
CYP1A2 P05177 2/20 0.40
HDAC7 Q8WUI4 2/20 0.40
HDAC10 Q969S8 2/20 0.40
HDAC11 Q96DB2 2/20 0.40
HDAC9 Q9UKV0 2/20 0.40
HDAC5 Q9UQL6 2/20 0.40
PLIN1 O60240 2/20 0.40
LMNA P02545 2/20 0.40
PLIN5 Q00G26 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL188344 0.86 GLA (0.48) GLATDP1HDAC3HDAC4HDAC1
SCHEMBL194943 0.86 GLA (0.48) GLATDP1HDAC3HDAC4HDAC1
SCHEMBL27523232 0.86 HDAC1 (0.42) GLATDP1HDAC3HDAC4HDAC1
SCHEMBL25215190 0.86 GLA (0.52) GLATDP1HDAC3HDAC4HDAC1
SCHEMBL23902289 0.86 GLA (0.52) GLATDP1HDAC3HDAC4HDAC1
SCHEMBL5550879 0.85 GLA (0.47) GLATDP1HDAC3HDAC4HDAC1
Methacrylic Acid SCHEMBL20959691 0.83 GLA (0.46) GLATDP1HDAC3HDAC4HDAC1
Methacrylic Acid SCHEMBL20959690 0.83 GLA (0.46) GLATDP1HDAC3HDAC4HDAC1
SCHEMBL3868471 0.82 HDAC1 (0.52) GLATDP1HDAC3HDAC4HDAC1
SCHEMBL3868467 0.82 HDAC1 (0.52) GLATDP1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112542231-A MapReduce and big data-based management method and system for number of cases for surgical prophylaxis 杭州杏林信息科技有限公司 2021-03-23 CN disclosed