Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.52 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20812755 | 0.82 | CRBN (0.47) | CRBNDDB1 | |
| SCHEMBL20812754 | 0.81 | CRBN (0.58) | CRBNDDB1 | |
| SCHEMBL4388041 | 0.81 | CRBN (0.56) | CRBNDDB1IKZF3 | |
| SCHEMBL4388040 | 0.81 | CRBN (0.56) | CRBNDDB1IKZF3 | |
| SCHEMBL4399379 | 0.81 | CRBN (0.56) | CRBNDDB1IKZF3 | |
| SCHEMBL7130014 | 0.79 | CRBN (0.54) | CRBNDDB1IKZF3 | |
| SCHEMBL7130010 | 0.79 | CRBN (0.54) | CRBNDDB1IKZF3 | |
| SCHEMBL4778728 | 0.74 | CRBN (0.74) | CRBNDDB1IKZF3 | |
| SCHEMBL20812385 | 0.72 | CRBN (0.49) | CRBNDDB1 | |
| SCHEMBL5742870 | 0.72 | CRBN (0.59) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892577-B | Compounds and methods for androgen receptor targeted degradation | 阿尔维纳斯运营股份有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-111892577-A | Compounds and methods for targeted degradation of androgen receptor | 阿尔维纳斯运营股份有限公司 | 2020-11-06 | — | — | CN | disclosed |