Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 19/20 | 0.74 |
| ▸ | CDK4 | P11802 | 17/20 | 0.74 |
| ▸ | CSF1R | P07333 | 16/20 | 0.74 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.73 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.72 |
| ▸ | CDK2 | P24941 | 3/20 | 0.72 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.72 |
| ▸ | CCNK | O75909 | 1/20 | 0.70 |
| ▸ | CDK7 | P50613 | 1/20 | 0.70 |
| ▸ | CDK9 | P50750 | 1/20 | 0.70 |
| ▸ | CCNH | P51946 | 1/20 | 0.70 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.70 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21267581 | 0.87 | CDK6 (0.78) | CDK6CDK4CSF1RPIK3CDCCNA2 | |
| SCHEMBL21267691 | 0.86 | CDK6 (0.70) | CDK6CDK4CSF1RPIK3CDCCNA2 | |
| SCHEMBL21267465 | 0.85 | CDK6 (0.75) | CDK6CDK4CSF1RPIK3CDCCNA2 | |
| SCHEMBL30631229 | 0.85 | CDK6 (0.81) | CDK6CDK4CSF1RPIK3CDCCNA2 | |
| SCHEMBL27089931 | 0.85 | CDK6 (0.81) | CDK6CDK4CSF1RPIK3CDCCNA2 | |
| SCHEMBL21245703 | 0.85 | CDK6 (1.00) | CDK6CDK4CSF1RPIK3CDCCNA2 | |
| SCHEMBL21267130 | 0.85 | CDK6 (0.70) | CDK6CDK4CSF1RPIK3CDCCNA2 | |
| SCHEMBL30631112 | 0.85 | CDK6 (0.78) | CDK6CDK4CSF1RPIK3CDCCNA2 | |
| SCHEMBL26633423 | 0.85 | CDK6 (0.78) | CDK6CDK4CSF1RPIK3CDCCNA2 | |
| SCHEMBL21245658 | 0.85 | CDK6 (0.79) | CDK6CDK4CSF1RPIK3CDCCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112334451-A | Heterocyclic compounds as kinase inhibitors | 诺维逊生物股份有限公司 | 2021-02-05 | — | — | CN | disclosed |