SCHEMBL28534836

SCHEMBL28534836

CC1(C)C(NC(=O)NC(=O)c2ccc(N3CCNCC3)nc2)C(C)(C)C1Oc1ccc(C#N)c(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 20/20 0.57
CRBN Q96SW2 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28534834 1.00 AR (0.57) ARCRBN
SCHEMBL30460051 0.94 AR (0.65) ARCRBN
SCHEMBL21477124 0.94 AR (0.65) ARCRBN
SCHEMBL19580731 0.94 AR (0.65) ARCRBN
SCHEMBL19580734 0.94 AR (0.65) ARCRBN
Hydrochloric Acid SCHEMBL20423149 0.93 AR (0.64) ARCRBN
Hydrochloric Acid SCHEMBL30479999 0.93 AR (0.64) ARCRBN
Hydrochloric Acid SCHEMBL20423148 0.93 AR (0.64) ARCRBN
SCHEMBL20443104 0.85 AR (0.68) ARCRBN
SCHEMBL20046076 0.85 AR (0.61) ARCRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112262134-A Cereblon ligand and bifunctional compound comprising same 阿尔维纳斯运营股份有限公司 2021-01-22 CN disclosed