Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 1.00 |
| ▸ | LIFR | P42702 | 4/20 | 0.89 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | FABP1 | P07148 | 1/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.74 |
| ▸ | RECQL | P46063 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30080777 | 1.00 | NR1H4 (1.00) | NR1H4LIFRMEN1FABP1THRB | |
| SCHEMBL30080747 | 0.95 | NR1H4 (0.91) | NR1H4LIFRMEN1FABP1THRB | |
| SCHEMBL28523863 | 0.95 | NR1H4 (0.91) | NR1H4LIFRMEN1FABP1THRB | |
| SCHEMBL30080609 | 0.94 | NR1H4 (1.00) | NR1H4LIFRMEN1FABP1THRB | |
| SCHEMBL4598944 | 0.93 | NR1H4 (0.87) | NR1H4LIFRMEN1FABP1THRB | |
| SCHEMBL4426866 | 0.93 | NR1H4 (0.86) | NR1H4LIFRMEN1FABP1THRB | |
| SCHEMBL30080791 | 0.92 | NR1H4 (0.95) | NR1H4LIFR | |
| SCHEMBL21624441 | 0.90 | NR1H4 (1.00) | NR1H4LIFR | |
| SCHEMBL30080605 | 0.89 | NR1H4 (0.85) | NR1H4LIFR | |
| SCHEMBL21624446 | 0.89 | NR1H4 (1.00) | NR1H4LIFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424173-A | Isoxazoles as FXR receptor agonists | 巴尔制药有限公司 | 2021-02-26 | — | — | CN | disclosed |