Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.61 |
| ▸ | BTK | Q06187 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001948 | 0.94 | EGFR (0.64) | EGFRBTK | |
| SCHEMBL23421131 | 0.93 | EGFR (0.61) | EGFRBTK | |
| SCHEMBL25821590 | 0.93 | EGFR (0.56) | EGFR | |
| SCHEMBL23441985 | 0.92 | EGFR (0.71) | EGFR | |
| SCHEMBL23442894 | 0.92 | EGFR (0.62) | EGFRBTK | |
| SCHEMBL23759756 | 0.91 | EGFR (0.58) | EGFRBTK | |
| SCHEMBL23420836 | 0.91 | EGFR (0.68) | EGFR | |
| SCHEMBL23441988 | 0.90 | EGFR (0.52) | EGFRBTK | |
| SCHEMBL25002438 | 0.89 | EGFR (0.56) | EGFR | |
| SCHEMBL23420454 | 0.88 | EGFR (0.67) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538072-A | Novel aminopyrimidine EGFR (epidermal growth factor receptor) inhibitor | 齐鲁制药有限公司 | 2021-03-23 | — | — | CN | disclosed |