SCHEMBL28535697

SCHEMBL28535697

Cc1cc(S(=O)(=O)Nc2cscn2)ccc1N(C)C1CCNC1

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 20/20 0.62
SCN1A P35498 18/20 0.62
SCN5A Q14524 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19627690 0.90 SCN1A (0.64) SCN8ASCN1ASCN5A
SCHEMBL28526627 0.90 SCN1A (0.64) SCN8ASCN1ASCN5A
SCHEMBL19613872 0.88 SCN8A (0.64) SCN8ASCN1ASCN5A
SCHEMBL19613873 0.88 SCN8A (0.64) SCN8ASCN1ASCN5A
SCHEMBL21789138 0.86 SCN8A (0.61) SCN8ASCN1A
SCHEMBL21789096 0.85 SCN8A (0.63) SCN8ASCN1A
SCHEMBL28519890 0.83 SCN8A (0.67) SCN8ASCN1A
SCHEMBL19627655 0.83 SCN8A (0.67) SCN8ASCN1A
Trifluoroacetic Acid SCHEMBL19614081 0.83 SCN1A (0.59) SCN8ASCN1ASCN5A
Trifluoroacetic Acid SCHEMBL19614080 0.83 SCN1A (0.59) SCN8ASCN1ASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109526219-B Benzenesulfonamides and their use as therapeutic agents 泽农医药公司 2021-03-12 CN disclosed