Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 17/20 | 0.71 |
| ▸ | CHRM3 | P20309 | 17/20 | 0.71 |
| ▸ | CHRM5 | P08912 | 13/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28544151 | 0.88 | CHRM1 (0.56) | CHRM1CHRM3CHRM5CHRM2 | |
| SCHEMBL28536543 | 0.86 | CHRM1 (0.54) | CHRM1CHRM3CHRM5CHRM2 | |
| SCHEMBL28542085 | 0.80 | CHRM1 (0.49) | CHRM1CHRM3CHRM5CHRM2 | |
| SCHEMBL14335155 | 0.77 | CHRM1 (0.57) | CHRM1CHRM3CHRM5CHRM2SIGMAR1 | |
| SCHEMBL14335152 | 0.77 | CHRM1 (0.57) | CHRM1CHRM3CHRM5CHRM2SIGMAR1 | |
| SCHEMBL3355641 | 0.77 | HTR2A (0.54) | CHRM1CHRM3CHRM5CHRM2SIGMAR1 | |
| SCHEMBL3341171 | 0.76 | SLC18A3 (0.55) | CHRM1CHRM3CHRM5CHRM2SIGMAR1 | |
| SCHEMBL743904 | 0.76 | CHRM2 (0.44) | CHRM1CHRM3CHRM5CHRM2SIGMAR1 | |
| SCHEMBL4807309 | 0.76 | PTGDR2 (0.46) | CHRM1CHRM3CHRM5CHRM2SIGMAR1 | |
| SCHEMBL4807302 | 0.76 | PTGDR2 (0.46) | CHRM1CHRM3CHRM5CHRM2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107080747-B | Glucosylceramide synthase inhibitors | 建新公司 | 2021-02-26 | — | — | CN | disclosed |