Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 3/20 | 0.68 |
| ▸ | SYK | P43405 | 11/20 | 0.51 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 4/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 3/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28541022 | 0.86 | NR4A1 (0.73) | NR4A1SYKABL1EGFRSRC | |
| SCHEMBL28553673 | 0.85 | NR4A1 (0.67) | NR4A1SYKABL1EGFRSRC | |
| SCHEMBL28377494 | 0.83 | NR4A1 (0.83) | NR4A1SYKABL1EGFRSRC | |
| SCHEMBL28376597 | 0.82 | NR4A1 (0.71) | NR4A1SYKABL1EGFRSRC | |
| SCHEMBL28546571 | 0.82 | NR4A1 (0.66) | NR4A1SYKABL1EGFRSRC | |
| SCHEMBL28541659 | 0.81 | NR4A1 (1.00) | NR4A1SYKABL1EGFRSRC | |
| SCHEMBL28911290 | 0.80 | NR4A1 (0.78) | NR4A1SYKABL1EGFRSRC | |
| SCHEMBL28375483 | 0.80 | NR4A1 (0.85) | NR4A1SYKABL1EGFRSRC | |
| SCHEMBL28546576 | 0.80 | NR4A1 (0.58) | NR4A1SYK | |
| SCHEMBL28376014 | 0.79 | ABL1 (0.67) | NR4A1SYKABL1EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734708-B | Pyrimidine indole Nur77 receptor regulator and preparation method and application thereof | 厦门大学 | 2021-04-09 | — | — | CN | disclosed |