Sulfamate

Sulfamate

SCHEMBL28537008

NS(=O)(=O)O.O=C(OCCCCO)c1cccc(C(=O)OCCCCO)c1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.53
CYP4F2 P78329 2/20 0.47
CYP4A11 Q02928 2/20 0.47
SLC7A5 Q01650 1/20 0.46
STS P08842 7/20 0.45
HDAC6 Q9UBN7 1/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA12 O43570 1/20 0.44
CA4 P22748 1/20 0.44
CA9 Q16790 1/20 0.44
SERPINE1 P05121 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfamate SCHEMBL28550984 0.98 TDP1 (0.51) TDP1CYP4F2CYP4A11SLC7A5STS
SCHEMBL1104296 0.91 TDP1 (0.63) TDP1CYP4F2CYP4A11SLC7A5HDAC6
SCHEMBL21143362 0.89 TDP1 (0.61) TDP1CYP4F2CYP4A11SLC7A5HDAC6
SCHEMBL3877623 0.89 TDP1 (0.61) TDP1CYP4F2CYP4A11SLC7A5HDAC6
Sulfamate SCHEMBL28551332 0.87 STS (0.56) TDP1STSHDAC6CA1CA2
SCHEMBL1475118 0.86 TDP1 (0.62) TDP1CYP4F2CYP4A11SLC7A5HDAC6
Sulfamate SCHEMBL28549033 0.86 STS (0.57) TDP1STSHDAC6CA1CA2
SCHEMBL3088431 0.85 TDP1 (0.60) TDP1CYP4F2CYP4A11SLC7A5HDAC6
SCHEMBL5790462 0.85 TDP1 (0.51) TDP1CYP4F2CYP4A11SLC7A5CA1
SCHEMBL1474816 0.84 TDP1 (0.61) TDP1CYP4F2CYP4A11SLC7A5HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109734871-B Preparation method of polyurethane emulsion with low water absorption and high solid content 沈阳化工研究院有限公司 2021-04-13 CN disclosed