Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.47 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28542060 | 0.87 | PTGDR2 (0.50) | PTGDR2ERN1TDP1APPCYP2C9 | |
| SCHEMBL10623779 | 0.82 | APP (0.50) | PTGDR2ERN1TDP1APPCYP2C9 | |
| SCHEMBL10620408 | 0.80 | APP (0.48) | PTGDR2ERN1TDP1APPCYP2C9 | |
| SCHEMBL15895560 | 0.80 | ERN1 (0.44) | PTGDR2ERN1TDP1APPCYP2C9 | |
| SCHEMBL15895659 | 0.80 | FFAR1 (0.44) | PTGDR2APPCYP2C9FFAR1NPC1 | |
| SCHEMBL29857390 | 0.80 | SRC (0.41) | ERN1TDP1APPCYP2C9FFAR1 | |
| SCHEMBL28574515 | 0.80 | SRC (0.41) | ERN1TDP1APPCYP2C9FFAR1 | |
| SCHEMBL28544000 | 0.79 | TDP1 (0.41) | PTGDR2ERN1TDP1CYP2C9FFAR1 | |
| SCHEMBL28538274 | 0.79 | KCNH2 (0.45) | PTGDR2ERN1TDP1CYP2C9MEN1 | |
| SCHEMBL29238522 | 0.79 | FFAR1 (0.41) | PTGDR2ERN1APPCYP2C9FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903053-A | Synthesis method and application of diaryl azepine compound | 河南工业大学 | 2024-04-19 | — | — | CN | claimed |
| CN-117903053-A | Synthesis method and application of diaryl azepine compound | 河南工业大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-109810112-B | Preparation method of indolo [2,1-a ] phthalazine derivative | 华侨大学 | 2021-03-23 | — | — | CN | disclosed |