⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4903181 | 0.74 | — | — | |
| SCHEMBL1441894 | 0.74 | — | — | |
| SCHEMBL9764673 | 0.74 | — | — | |
| SCHEMBL1459722 | 0.72 | — | — | |
| SCHEMBL262103 | 0.72 | — | — | |
| SCHEMBL1775067 | 0.72 | — | — | |
| SCHEMBL3589631 | 0.72 | — | — | |
| SCHEMBL12497498 | 0.70 | — | — | |
| SCHEMBL11157039 | 0.69 | — | — | |
| SCHEMBL3726216 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103237801-B | Quinoline or quinazoline derivatives having apoptosis-inducing activity on cells | HANMI HOLDINGS Co.,Ltd. (KR) | 2015-11-25 | — | — | CN | claimed |
| US-20250382277-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | UNIV ARIZONA (US) | 2025-12-18 | — | — | US | disclosed |
| EP-4543887-A2 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | Arizona Board of Regents on behalf of The University of Arizona (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-117926291-A | Method for preparing bromoarene by taking bromopollutant as bromine source through photoelectrocatalysis | 中国科学院化学研究所 | 2024-04-26 | — | — | CN | disclosed |
| WO-2023250082-A2 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-12-28 | — | — | WO | disclosed |
| CN-104774188-B | Benzo-heterocycle or benzo hetero-aromatic ring analog derivative, preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-104892582-B | Azetidine as the mek inhibitor for treating proliferative disease | 埃克塞利希斯股份有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-110267953-A | Tetrahydroimidazo [4,5-C ] pyridine derivatives as inducers of PD-L1 internalization | 因赛特公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110251498-A | One kind adjusts active compound of Farnesoid X receptor and application thereof | 厦门大学 | 2019-09-20 | — | — | CN | disclosed |
| CN-106518845-B | Kynurenin -3- monooxygenase inhibitor, pharmaceutical composition and its application method | CHDI基金会股份有限公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-102985422-A | Pyrrolopyridine and pyrrolopyrimidine inhibitors of kinases | ABBVIE INC | 2013-03-20 | — | — | CN | disclosed |
| US-8263585-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-09-11 | — | — | US | disclosed |
| US-8183385-B2 | SNAR process for preparing benzimidazole compounds | ARRAY BIOPHARMA INC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-20100130748-A1 | SNAR PROCESS FOR PREPARING BENZIMIDAZOLE COMPOUNDS | ARRAY BIOPHARMA INC. (US) | 2010-05-27 | — | — | US | disclosed |
| US-20090163463-A1 | Organic Compounds | NOVARTIS AG | 2009-06-25 | — | — | US | disclosed |
| EP-2057140-A1 | MORPHOLINO PYRIMIDINE DERIVATIVES USEFUL IN THE TREATMENT OF PROLIFERATIVE DISORDERS | AstraZeneca AB (SE) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008089051-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES: PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-24 | — | — | WO | disclosed |
| EP-1904061-A1 | SNAr PROCESS FOR PREPARING BENZIMIDAZOLE COMPOUNDS | Array Biopharma, Inc. (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2008023159-A1 | MORPHOLINO PYRIMIDINE DERIVATIVES USEFUL IN THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2008-02-28 | — | — | WO | disclosed |
| WO-2007002092-A1 | SNAr PROCESS FOR PREPARING BENZIMIDAZOLE COMPOUNDS | ARRAY BIOPHARMA INC. (US) | 2007-01-04 | — | — | WO | disclosed |