Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.71 |
| ▸ | PIK3CD | O00329 | 17/20 | 0.71 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.71 |
| ▸ | PIK3CB | P42338 | 14/20 | 0.71 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.62 |
| ▸ | GAK | O14976 | 1/20 | 0.62 |
| ▸ | PRKACG | P22612 | 1/20 | 0.62 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11938366 | 0.94 | PIK3CA (0.79) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL11938365 | 0.92 | PIK3CA (0.75) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL11938367 | 0.92 | PIK3CA (0.78) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL11938363 | 0.90 | PIK3CA (0.77) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL11938402 | 0.88 | PIK3CA (0.71) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL28529212 | 0.87 | PIK3CA (0.66) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL11938399 | 0.86 | PIK3CA (0.75) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL11938381 | 0.84 | PIK3CA (0.77) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL11938376 | 0.83 | PIK3CA (0.75) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL13457883 | 0.82 | PIK3CA (0.95) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112472699-A | Combination methods for improving the therapeutic benefit of bisantrene and derivatives | 种族肿瘤学公司 | 2021-03-12 | — | — | CN | disclosed |