Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.51 |
| ▸ | KCNA3 | P22001 | 5/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076361 | 0.88 | ERAP1 (0.51) | ERAP1KCNA3CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL3091877 | 0.79 | ERAP1 (0.58) | ERAP1CYP1A1CYP1A2CYP1B1KDM4E | |
| SCHEMBL28538536 | 0.78 | MCL1 (0.53) | ERAP1KCNA3CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL12813584 | 0.75 | ESR2 (0.42) | ERAP1KCNA3KDM4ENPC1ALDH1A1 | |
| SCHEMBL3067421 | 0.75 | ERAP1 (0.52) | ERAP1KCNA3CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL18788967 | 0.74 | KCNA3 (0.60) | ERAP1KCNA3KDM4EALDH1A1 | |
| SCHEMBL28540828 | 0.73 | ERAP1 (0.45) | ERAP1KCNA3CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL5085541 | 0.72 | ERAP1 (0.47) | ERAP1KDM4ENPC1ALDH1A1KMT2A | |
| SCHEMBL18073992 | 0.71 | KCNA3 (0.67) | ERAP1KCNA3CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL4449250 | 0.71 | ERAP1 (0.68) | ERAP1CYP1A1CYP1A2CYP1B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107973768-B | Method for synthesizing coumarin compound in one step | 江苏欣诺科催化剂有限公司 | 2020-11-10 | — | — | CN | disclosed |