Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GCG | P01275 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 3/20 | 0.41 |
| ▸ | PMM2 | O15305 | 2/20 | 0.41 |
| ▸ | MPI | P34949 | 2/20 | 0.41 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28748687 | 0.88 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AGCG | |
| SCHEMBL28967464 | 0.83 | MEN1 (0.49) | NPC1RAB9AMEN1KMT2AGCG | |
| SCHEMBL28792823 | 0.81 | MEN1 (0.50) | NPC1RAB9AMEN1KMT2AGCG | |
| SCHEMBL28539532 | 0.80 | ESR2 (0.46) | NPC1RAB9AGCGADORA3KDM4E | |
| SCHEMBL11901390 | 0.80 | ESR2 (0.62) | NPC1RAB9AMEN1KMT2AGCG | |
| SCHEMBL28553007 | 0.80 | ESR2 (0.66) | NPC1RAB9AMEN1KMT2AGCG | |
| SCHEMBL9114545 | 0.79 | ESR2 (0.57) | NPC1RAB9AMEN1KMT2AADORA3 | |
| SCHEMBL3131684 | 0.79 | ESR2 (0.60) | NPC1RAB9AMEN1KMT2AADORA3 | |
| SCHEMBL1872760 | 0.78 | HTT (0.57) | NPC1RAB9AMEN1KMT2AADORA3 | |
| SCHEMBL2264359 | 0.77 | ESR2 (0.43) | NPC1RAB9AMEN1KMT2AGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184598-A | Photocatalytic preparation method and application of N- (2-phenyl-2H-indazole-3-yl) benzamide compound | 河南师范大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-112574112-B | Method for synthesizing N-substituted 2H-indazole compound through oxidation | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-112574112-A | Method for synthesizing N-substituted 2H-indazole compound through green oxidation | 浙江工业大学 | 2021-03-30 | — | — | CN | disclosed |