Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13904180 | 0.82 | CHRM2 (0.37) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL16134085 | 0.80 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL12035330 | 0.80 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL3346214 | 0.77 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL7495990 | 0.77 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL1169394 | 0.77 | MAPT (0.52) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL7499029 | 0.77 | — | — | |
| SCHEMBL16690749 | 0.76 | MAPT (0.41) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL19018901 | 0.76 | MAPT (0.41) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL21909908 | 0.76 | MAPT (0.41) | MAPTALDH1A1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709323-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2020-11-20 | — | — | CN | disclosed |