Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6128924 | 0.82 | TSHR (0.46) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| SCHEMBL28212051 | 0.82 | TSHR (0.52) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| Methyl Alcohol SCHEMBL28080029 | 0.82 | TSHR (0.52) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| SCHEMBL19273 | 0.82 | — | — | |
| SCHEMBL5167665 | 0.82 | TSHR (0.54) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| SCHEMBL31267242 | 0.82 | TSHR (0.54) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| SCHEMBL565292 | 0.80 | TSHR (0.48) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| Chloromethane SCHEMBL28424741 | 0.80 | TSHR (0.50) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| Propene SCHEMBL27446435 | 0.80 | TSHR (0.50) | TSHRHPGDMAPTCACNA1BAPBA1 | |
| SCHEMBL3319338 | 0.80 | MAPT (0.52) | TSHRHPGDMAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836322-A | Reinforcing emulsion, preparation method and application thereof | 山东京博中聚新材料有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-116444698-A | Method for preparing large-particle-size high-solid-content conjugated diene latex | 山东京博中聚新材料有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-114524902-A | Insect-attracting board adhesive emulsion and preparation method thereof | 上海昶法新材料有限公司 | 2022-05-24 | — | — | CN | claimed |
| CN-112552846-A | Water-based adhesive and preparation method thereof | 济宁明升新材料有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-112552847-A | Water-based adhesive and preparation method thereof | 济宁明升新材料有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-112151802-A | Negative electrode binder for lithium ion battery, preparation method of negative electrode binder and lithium ion battery containing negative electrode binder | 宜昌虎柏新能源有限公司 | 2020-12-29 | — | — | CN | claimed |
| CN-117186782-A | Efficient production process of PVB film and PVB film thereof | 乐凯光电材料有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-116836322-A | Reinforcing emulsion, preparation method and application thereof | 山东京博中聚新材料有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116444698-A | Method for preparing large-particle-size high-solid-content conjugated diene latex | 山东京博中聚新材料有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114195946-A | Printed carpet adhesive and preparation method thereof | 上海昶法新材料有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-113736002-A | Modified polyhalogenated styrene-1, 3-butadiene emulsion binder, preparation and application thereof | 江西迪比科股份有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-112552847-A | Water-based adhesive and preparation method thereof | 济宁明升新材料有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112151802-A | Negative electrode binder for lithium ion battery, preparation method of negative electrode binder and lithium ion battery containing negative electrode binder | 宜昌虎柏新能源有限公司 | 2020-12-29 | — | — | CN | disclosed |