Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27853144 | 0.86 | HDAC3 (0.67) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28968193 | 0.86 | HDAC3 (0.67) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28973854 | 0.86 | HDAC3 (0.67) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5145338 | 0.86 | HDAC3 (0.67) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27530055 | 0.86 | HDAC3 (0.67) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1262591 | 0.84 | HDAC3 (0.64) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28797730 | 0.81 | HDAC3 (0.48) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| Terephthalamide SCHEMBL28497793 | 0.81 | MEN1 (0.67) | HDAC6NPC1RAB9ASMN1; SMN2KMT2A | |
| Terephthalamide SCHEMBL17074059 | 0.81 | MEN1 (0.67) | HDAC6NPC1RAB9ASMN1; SMN2KMT2A | |
| Terephthalamide SCHEMBL28398318 | 0.81 | MEN1 (0.67) | HDAC6NPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538167-B | Alkyl chain modified acylhydrazone bond-linked covalent organic framework material and application thereof in photocatalytic hydrogen peroxide production | 福州大学 | 2021-08-31 | — | — | CN | disclosed |
| CN-112538167-A | Alkyl chain modified acylhydrazone bond-linked covalent organic framework material and application thereof in photocatalytic hydrogen peroxide production | 福州大学 | 2021-03-23 | — | — | CN | disclosed |