Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13528913 | 0.97 | GSK3B (0.46) | GSK3BCHRNA7HTR3AHTR3EHTR3B | |
| SCHEMBL2856715 | 0.97 | GSK3B (0.46) | GSK3BCHRNA7HTR3AHTR3EHTR3B | |
| SCHEMBL2856720 | 0.97 | GSK3B (0.46) | GSK3BCHRNA7HTR3AHTR3EHTR3B | |
| Formic Acid SCHEMBL2855400 | 0.93 | GSK3B (0.51) | GSK3BCHRNA7HTR3AHTR3EHTR3B | |
| SCHEMBL2855652 | 0.90 | GSK3B (0.53) | GSK3BCHRNA7HTR3AHTR3EHTR3B | |
| SCHEMBL2855656 | 0.90 | GSK3B (0.53) | GSK3BCHRNA7HTR3AHTR3EHTR3B | |
| SCHEMBL1963432 | 0.80 | CHRNA7 (0.62) | GSK3BCHRNA7HTR3APAK1USP30 | |
| SCHEMBL1963273 | 0.80 | CHRNA7 (0.62) | GSK3BCHRNA7HTR3APAK1USP30 | |
| Formic Acid SCHEMBL2853995 | 0.80 | CHRNA7 (0.41) | CHRNA7HTR3AHTR3EHTR3BCHRNB2 | |
| Hydrochloric Acid SCHEMBL1964985 | 0.80 | CHRNA7 (0.61) | GSK3BCHRNA7HTR3AUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828179-B1 | NICOTINIC ALPHA-7 RECEPTOR LIGANDS AGAINST CNS-RELATED DISEASES | MEMORY PHARM CORP (US) | 2010-01-20 | — | — | EP | claimed |