SCHEMBL28542255

SCHEMBL28542255

CC(=O)NCC1CCN(Cc2cc(Oc3ccc(N4CCN(CCO[PH](=O)OCCN5CCN(c6ccc(Oc7cc(CN8CCC(CNC(C)=O)CC8)cc(-c8cc(Cl)cc(Cl)c8)n7)cn6)CC5)CC4)nc3)nc(-c3cc(Cl)cc(Cl)c3)c2)CC1

nearest known ligand 0.86

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28542258 0.95 FURIN (0.85) FURIN
SCHEMBL21550971 0.93 FURIN (1.00) FURIN
SCHEMBL29928723 0.93 FURIN (1.00) FURIN
SCHEMBL21564526 0.92 FURIN (0.89) FURIN
SCHEMBL21550852 0.91 FURIN (1.00) FURIN
SCHEMBL29928831 0.91 FURIN (1.00) FURIN
SCHEMBL26077319 0.91 FURIN (0.90) FURIN
SCHEMBL21551576 0.91 FURIN (0.86) FURIN
SCHEMBL29927940 0.91 FURIN (0.86) FURIN
SCHEMBL21550910 0.91 FURIN (0.88) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112384509-B Furin inhibitors 葛兰素史密斯克莱知识产权发展有限公司 2024-04-30 — — CN disclosed
CN-112384509-A Furin inhibitors 葛兰素史密斯克莱知识产权发展有限公司 2021-02-19 — — CN disclosed
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