Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | PON1 | P27169 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23698417 | 1.00 | NPC1 (0.51) | NPC1RAB9AHTTSMN1; SMN2HSP90AA1 | |
| SCHEMBL21834756 | 1.00 | NPC1 (0.51) | NPC1RAB9AHTTSMN1; SMN2HSP90AA1 | |
| SCHEMBL23698381 | 1.00 | NPC1 (0.51) | NPC1RAB9AHTTSMN1; SMN2HSP90AA1 | |
| SCHEMBL21834759 | 1.00 | NPC1 (0.51) | NPC1RAB9AHTTSMN1; SMN2HSP90AA1 | |
| SCHEMBL23698569 | 1.00 | NPC1 (0.51) | NPC1RAB9AHTTSMN1; SMN2HSP90AA1 | |
| Bromide SCHEMBL1884396 | 0.98 | NPC1 (0.54) | NPC1RAB9AHTTSMN1; SMN2HSP90AA1 | |
| Bromide SCHEMBL1885380 | 0.98 | NPC1 (0.54) | NPC1RAB9AHTTSMN1; SMN2HSP90AA1 | |
| Bromide SCHEMBL1879504 | 0.98 | NPC1 (0.54) | NPC1RAB9AHTTSMN1; SMN2HSP90AA1 | |
| Bromide SCHEMBL1885921 | 0.98 | NPC1 (0.54) | NPC1RAB9AHTTSMN1; SMN2HSP90AA1 | |
| Bromide SCHEMBL1881356 | 0.98 | NPC1 (0.54) | NPC1RAB9AHTTSMN1; SMN2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112703184-A | Process for producing amide compound, and amide compound | 广荣化学株式会社 | 2021-04-23 | — | — | CN | disclosed |