Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 3/20 | 0.62 |
| ▸ | NAT1 | P18440 | 4/20 | 0.43 |
| ▸ | MYC | P01106 | 2/20 | 0.40 |
| ▸ | IL1RN | P18510 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.38 |
| ▸ | MAX | P61244 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28964144 | 0.79 | PTP4A3 (1.00) | PTP4A3NAT1MYCCA2EPHX1 | |
| SCHEMBL28564746 | 0.77 | PIM1 (0.49) | PTP4A3NAT1MYCIL1RNERAP1 | |
| SCHEMBL13499576 | 0.66 | PTP4A3 (0.72) | PTP4A3NAT1MYCCA2EPHX1 | |
| SCHEMBL13499579 | 0.65 | PTP4A3 (0.67) | PTP4A3NAT1MYCCA2EPHX1 | |
| SCHEMBL13499577 | 0.65 | NAT1 (0.64) | PTP4A3NAT1MYCCA2DNM1 | |
| SCHEMBL9405061 | 0.65 | PTP4A3 (0.66) | PTP4A3NAT1MYCCA2EPHX1 | |
| SCHEMBL18102956 | 0.64 | PIK3CG (0.67) | PTP4A3NAT1MYCCA2EPHX1 | |
| SCHEMBL632171 | 0.64 | GRM5 (0.59) | MEN1NPC1ALDH1A1LMNAPOLB | |
| SCHEMBL13499560 | 0.64 | PTP4A3 (0.65) | PTP4A3NAT1MYCCA2EPHX1 | |
| SCHEMBL3405858 | 0.63 | PTP4A3 (0.71) | PTP4A3NAT1MYCCISD1MAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428718-B | Preparation method of brexpiprazole analogue | 苏州旺山旺水生物医药有限公司 | 2021-04-27 | — | — | CN | disclosed |