Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2539328 | 0.89 | NPC1 (0.48) | HRH4MEN1KMT2AALDH1A1PIK3CA | |
| SCHEMBL1698726 | 0.80 | HRH4 (0.54) | HRH4MEN1KMT2AALDH1A1GAA | |
| SCHEMBL15511394 | 0.80 | HRH4 (0.54) | HRH4MEN1KMT2AALDH1A1GAA | |
| SCHEMBL733377 | 0.80 | MEN1 (0.47) | MEN1KMT2AMAPK10ALDH1A1HTR2C | |
| Ethylene SCHEMBL29031103 | 0.78 | HRH4 (0.51) | HRH4MEN1KMT2AALDH1A1GAA | |
| SCHEMBL19616081 | 0.77 | JMJD6 (0.49) | MEN1KMT2AALDH1A1PIK3CAJMJD6 | |
| SCHEMBL18135117 | 0.77 | HRH4 (0.50) | HRH4MEN1KMT2AHTR2CGAA | |
| SCHEMBL31706848 | 0.76 | NPC1 (0.50) | ALDH1A1GAATP53BP1 | |
| SCHEMBL1516956 | 0.76 | PIK3CA (0.75) | HRH4MEN1KMT2AMAPK10ALDH1A1 | |
| SCHEMBL2384044 | 0.76 | JMJD6 (0.49) | HRH4ALDH1A1JMJD6TP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925357-B | Acylhydrazone compound, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2023-06-06 | — | — | CN | disclosed |
| CN-111925357-A | Acylhydrazone compound, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2020-11-13 | — | — | CN | disclosed |