Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 19/20 | 0.64 |
| ▸ | SCN8A | Q9UQD0 | 19/20 | 0.64 |
| ▸ | SCN5A | Q14524 | 17/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28555288 | 0.88 | SCN1A (0.63) | SCN1ASCN8ASCN5ACYP3A4CD38 | |
| Trifluoroacetic Acid SCHEMBL21955501 | 0.80 | SCN8A (0.89) | SCN1ASCN8ASCN5A | |
| SCHEMBL21783421 | 0.78 | SCN8A (1.00) | SCN1ASCN8ASCN5A | |
| Trifluoroacetic Acid SCHEMBL21955468 | 0.72 | SCN1A (0.89) | SCN1ASCN8ASCN5A | |
| Trifluoroacetic Acid SCHEMBL30046854 | 0.72 | SCN1A (0.89) | SCN1ASCN8ASCN5A | |
| SCHEMBL20238835 | 0.71 | SCN8A (0.63) | SCN1ASCN8ASCN5ACYP3A4 | |
| SCHEMBL28911218 | 0.71 | SCN8A (0.65) | SCN1ASCN8ASCN5ACYP3A4 | |
| SCHEMBL21783425 | 0.70 | SCN8A (0.68) | SCN1ASCN8ASCN5A | |
| SCHEMBL21783382 | 0.70 | SCN1A (1.00) | SCN1ASCN8ASCN5A | |
| SCHEMBL28549795 | 0.69 | SCN8A (0.66) | SCN1ASCN8ASCN5ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638879-B | Heteroaryl substituted sulfonamide compounds and their use as therapeutic agents | 泽农医药公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-112638879-A | Heteroaryl substituted sulfonamide compounds and their use as therapeutic agents | 泽农医药公司 | 2021-04-09 | — | — | CN | disclosed |