Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.60 |
| ▸ | CCNK | O75909 | 2/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 3/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23292284 | 1.00 | CDK12 (0.60) | CDK12CCNKUSP30PIK3CDBTK | |
| SCHEMBL22895718 | 1.00 | CDK12 (0.60) | CDK12CCNKUSP30PIK3CDBTK | |
| SCHEMBL28550665 | 0.89 | CDK12 (0.60) | CDK12CCNKUSP30BTKTRPV1 | |
| SCHEMBL23292355 | 0.89 | CDK12 (0.60) | CDK12CCNKUSP30BTKTRPV1 | |
| SCHEMBL22895525 | 0.89 | CDK12 (0.60) | CDK12CCNKUSP30BTKTRPV1 | |
| SCHEMBL22895338 | 0.84 | CDK12 (0.59) | CDK12CCNKUSP30PIK3CDBTK | |
| SCHEMBL23292383 | 0.84 | CDK12 (0.59) | CDK12CCNKUSP30PIK3CDBTK | |
| SCHEMBL9942554 | 0.84 | USP30 (0.46) | CDK12USP30PIK3CDBTKTRPV1 | |
| SCHEMBL9899889 | 0.84 | USP30 (0.46) | CDK12USP30PIK3CDBTKTRPV1 | |
| SCHEMBL28571259 | 0.82 | BTK (0.43) | CDK12CCNKUSP30PIK3CDBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |