Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK12 | Q9NYV4 | 9/20 | 0.56 |
| ▸ | CCNK | O75909 | 8/20 | 0.56 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.45 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23292333 | 1.00 | CDK12 (0.56) | CDK12CCNKUSP30MAPK8MAPK9 | |
| SCHEMBL22895770 | 1.00 | CDK12 (0.56) | CDK12CCNKUSP30MAPK8MAPK9 | |
| SCHEMBL22895533 | 0.90 | USP30 (0.52) | CDK12CCNKUSP30MAPK8MAPK9 | |
| SCHEMBL23292274 | 0.90 | USP30 (0.52) | CDK12CCNKUSP30MAPK8MAPK9 | |
| SCHEMBL28552023 | 0.90 | USP30 (0.52) | CDK12CCNKUSP30MAPK8MAPK9 | |
| SCHEMBL28546426 | 0.88 | USP30 (0.50) | CDK12CCNKUSP30MAPK8MAPK9 | |
| SCHEMBL28546428 | 0.88 | USP30 (0.50) | CDK12CCNKUSP30MAPK8MAPK9 | |
| SCHEMBL23292466 | 0.88 | USP30 (0.50) | CDK12CCNKUSP30MAPK8MAPK9 | |
| SCHEMBL23325385 | 0.88 | CCNK (0.61) | CDK12CCNKCDK13 | |
| SCHEMBL22895516 | 0.88 | CCNK (0.61) | CDK12CCNKCDK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |