Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28541058 | 0.86 | MAPT (0.50) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL28799385 | 0.85 | MAPT (0.38) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28799409 | 0.84 | CYP1A2 (0.42) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28551878 | 0.84 | CA12 (0.45) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28799426 | 0.84 | PTGDR2 (0.38) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28799402 | 0.84 | FFAR1 (0.39) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL30209793 | 0.81 | PTGDR2 (0.38) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28545613 | 0.81 | APP (0.49) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL30209791 | 0.80 | RARB (0.40) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28356528 | 0.78 | FFAR1 (0.55) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736181-B | Synthesis method of visible light mediated acylated benzofuran derivative | 河南大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-114805268-B | Synthesis method of visible light mediated cyclopenta [ b ] benzofuran derivative | 河南大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-110272403-B | Method for synthesizing carbamate containing dihydrobenzofuran ring and trifluoromethyl | 华南理工大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-115626904-A | 3-enamide substituted benzodihydrofuran compound and preparation method thereof | 华南理工大学 | 2023-01-20 | — | — | CN | disclosed |
| CN-112442002-B | Method for synthesizing 11-sulfenyl naphtho [2,3-b ] benzofuran compound | 桂林医学院 | 2022-09-20 | — | — | CN | disclosed |
| CN-114805268-A | Synthesis method of visible light mediated cyclopenta [ b ] benzofuran derivative | 河南大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114736181-A | Synthesis method of visible light mediated acylated benzofuran derivative | 河南大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-112442002-A | Method for synthesizing 11-sulfenyl naphtho [2,3-b ] benzofuran compound | 桂林医学院 | 2021-03-05 | — | — | CN | disclosed |