Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839770 | 0.82 | MAOB (0.44) | SGMS2ADRA2AADRA2BADRA2CMAOB | |
| SCHEMBL3767200 | 0.79 | IDO1 (0.51) | MAPTNPSR1SGMS2 | |
| SCHEMBL3326060 | 0.79 | IDO1 (0.48) | L3MBTL1MAPTNPSR1KDM4EMAOB | |
| SCHEMBL27822794 | 0.79 | IDO1 (0.48) | MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL2721265 | 0.79 | IDO1 (0.48) | MAPTHPGDMAOB | |
| SCHEMBL5790467 | 0.79 | TP53 (0.40) | L3MBTL1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL11567089 | 0.79 | IDO1 (0.48) | KDM4E | |
| SCHEMBL3974783 | 0.78 | MAOB (0.35) | MAPTKDM4ENISCHMAOB | |
| SCHEMBL5539771 | 0.77 | MAPT (0.39) | L3MBTL1MAPTKDM4EHPGDMAOB | |
| SCHEMBL49802 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108329330-B | 2-benzyloxy phenyl oxazolopyridine compound and pharmaceutical application thereof | 复旦大学 | 2021-05-04 | — | — | CN | disclosed |