SCHEMBL28546351

SCHEMBL28546351

Cc1cccc(OP(=O)(O)OP(=O)(O)OP(=O)(O)O)c1C.O[Si](O)(O)Oc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
SRC P12931 3/20 0.36
GAA P10253 3/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
ALDH1A1 P00352 4/20 0.34
POLB P06746 3/20 0.34
CRHBP P24387 1/20 0.34
FNTA P49354 1/20 0.34
FNTB P49356 1/20 0.34
CRHR2 Q13324 1/20 0.34
KDM4E B2RXH2 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
HSD17B10 Q99714 2/20 0.31
USP2 O75604 1/20 0.31
HPGD P15428 1/20 0.31
PDE3A Q14432 1/20 0.31
INPPL1 O15357 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2185087 0.83 MAPT (0.59) MAPTSRCGAALMNAMAPK1
Triphosphate SCHEMBL28546306 0.80 SRC (0.48) SRCGAAALDH1A1POLBKDM4E
SCHEMBL4455352 0.78 MAPT (0.56) MAPTSRCGAALMNAMAPK1
SCHEMBL31299925 0.78 MAPT (0.56) MAPTSRCGAALMNAMAPK1
SCHEMBL11801740 0.74 SRC (0.44) MAPTSRCLMNAALDH1A1POLB
SCHEMBL28539555 0.74 CYP3A4 (0.45) MAPTSRCGAALMNAALDH1A1
SCHEMBL497309 0.74 MAPT (0.67) MAPTGAALMNAMAPK1HTT
Biphenyl SCHEMBL28011477 0.73 MAPT (0.57) MAPTGAALMNAMAPK1HTT
SCHEMBL7546964 0.72 MAPT (0.56) MAPTSRCGAALMNAMAPK1
Phenol SCHEMBL2452431 0.72 MAPT (0.56) MAPTSRCGAALMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109851952-B Environment-friendly low-smoke flame-retardant PVC material and preparation method and application thereof 浙江新铭隆科技有限公司 2021-04-06 CN claimed
CN-109851952-B Environment-friendly low-smoke flame-retardant PVC material and preparation method and application thereof 浙江新铭隆科技有限公司 2021-04-06 CN disclosed