Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.40 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | FURIN | P09958 | 6/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28551717 | 0.90 | MCHR1 (0.41) | MCHR1RETAAK1PDE10AFURIN | |
| SCHEMBL28539414 | 0.84 | CKS1B (0.48) | RETFURIN | |
| SCHEMBL29890855 | 0.84 | FURIN (0.39) | MCHR1RETAAK1PDE10AFURIN | |
| SCHEMBL21551603 | 0.82 | FURIN (0.39) | MCHR1RETAAK1PDE10AFURIN | |
| SCHEMBL21551605 | 0.81 | FURIN (0.41) | MCHR1RETAAK1FURINSCN9A | |
| SCHEMBL29890682 | 0.80 | FURIN (0.37) | MCHR1RETAAK1PDE10AFURIN | |
| SCHEMBL21564562 | 0.77 | CKS1B (0.44) | RETFURIN | |
| SCHEMBL29890729 | 0.77 | CKS1B (0.44) | RETFURIN | |
| SCHEMBL21551013 | 0.73 | CKS1B (0.46) | RETFURIN | |
| SCHEMBL595584 | 0.73 | AAK1 (0.47) | MCHR1RETAAK1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |