SCHEMBL28548192

SCHEMBL28548192

O=C(Nc1ccccc1)C(O)CO

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.55
HDAC2 Q92769 1/20 0.54
MAPT P10636 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
GAA P10253 2/20 0.50
ATM Q13315 2/20 0.50
EPHX2 P34913 2/20 0.50
TP53 P04637 1/20 0.50
EPHX1 P07099 1/20 0.50
TSHR P16473 1/20 0.50
CDK9 P50750 1/20 0.50
CLK4 Q9HAZ1 1/20 0.50
LMNA P02545 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
HPGD P15428 1/20 0.50
HTT P42858 1/20 0.50
HSP90AA1 P07900 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2735379 0.85 HDAC2 (0.59) POLBHDAC2MAPTMEN1KMT2A
SCHEMBL4594451 0.82 MEN1 (0.62) POLBHDAC2MAPTMEN1KMT2A
SCHEMBL28022968 0.82 POLB (0.53) POLBHDAC2MAPTMEN1KMT2A
SCHEMBL4888030 0.82 ROCK1 (0.54) POLBHDAC2MAPTMEN1KMT2A
SCHEMBL21056246 0.82 MEN1 (0.61) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL8269130 0.81 NPC1 (0.50) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL27729541 0.81 HDAC2 (0.38) POLBHDAC2MAPTMEN1KMT2A
SCHEMBL8864057 0.81 MEN1 (0.54) POLBHDAC2MAPTMEN1KMT2A
SCHEMBL4747179 0.79 POLB (0.50) POLBHDAC2MAPTMEN1KMT2A
SCHEMBL16964230 0.79 HDAC2 (0.57) POLBHDAC2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114555039-A Hair treatment composition 联合利华知识产权控股有限公司 2022-05-27 CN disclosed
CN-106687105-B Transparent cosmetic and personal care compositions 荷兰联合利华有限公司 2021-03-23 CN disclosed