Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28548278 | 1.00 | HDAC8 (0.33) | HDAC8HDAC1HDAC6ALDH1A1NPC1 | |
| SCHEMBL14247051 | 0.80 | HDAC8 (0.31) | HDAC8HDAC1HDAC6 | |
| SCHEMBL1186609 | 0.80 | HDAC8 (0.31) | HDAC8HDAC1HDAC6 | |
| SCHEMBL1186606 | 0.80 | HDAC8 (0.31) | HDAC8HDAC1HDAC6 | |
| SCHEMBL27636829 | 0.79 | HDAC8 (0.36) | HDAC8HDAC1HDAC6 | |
| SCHEMBL18587007 | 0.78 | — | — | |
| SCHEMBL18587005 | 0.78 | — | — | |
| SCHEMBL453485 | 0.76 | — | — | |
| SCHEMBL14246901 | 0.75 | — | — | |
| SCHEMBL12284475 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |