SCHEMBL28548600

SCHEMBL28548600

NC(=O)OCC1CCN(Cc2cc(Oc3ccc(N4CCNCC4)nc3)nc(-c3cc(Cl)cc(Cl)c3)c2)CC1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28543597 0.91 FURIN (0.68) FURIN
SCHEMBL21551591 0.91 FURIN (0.64) FURIN
SCHEMBL29928863 0.91 FURIN (0.64) FURIN
SCHEMBL28552037 0.90 FURIN (0.80) FURIN
SCHEMBL29928651 0.90 FURIN (0.81) FURIN
SCHEMBL21550606 0.90 FURIN (0.81) FURIN
SCHEMBL21551251 0.88 FURIN (0.70) FURIN
SCHEMBL28911587 0.88 FURIN (0.60) FURIN
SCHEMBL28539329 0.88 FURIN (0.62) FURIN
SCHEMBL25192768 0.88 FURIN (0.61) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115666567-A Furin inhibitors for the treatment of coronavirus infection BP资产V股份有限公司 2023-01-31 — — CN claimed
CN-114929220-A Small molecule furin inhibitors for the treatment of infectious diseases BP资产V股份有限公司 2022-08-19 — — CN claimed
CN-112384509-A Furin inhibitors 葛兰素史密斯克莱知识产权发展有限公司 2021-02-19 — — CN claimed
CN-112384509-B Furin inhibitors 葛兰素史密斯克莱知识产权发展有限公司 2024-04-30 — — CN disclosed
CN-112384509-A Furin inhibitors 葛兰素史密斯克莱知识产权发展有限公司 2021-02-19 — — CN disclosed
Send feedback