Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.47 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9612439 | 0.94 | ESR1 (0.48) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL13015708 | 0.93 | ESR1 (0.45) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL13015698 | 0.93 | ESR1 (0.45) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL27012986 | 0.93 | ESR1 (0.51) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL12144452 | 0.92 | ESR1 (0.48) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL26825359 | 0.91 | ESR1 (0.50) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL134057 | 0.91 | ESR1 (0.52) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL18999492 | 0.91 | PTGER4 (0.47) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL29444817 | 0.91 | ESR1 (0.52) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL13098744 | 0.91 | ESR1 (0.52) | ESR1ESR2GRIA1CACNG8CACNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993123-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-8993123-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-8993123-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20100327270-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| US-20100327270-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| US-20100327270-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| EP-2240425-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009100925-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100327270-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, ELAVL1, EPCAM | ESR1 387/4885ESR2 320/4885GRIA1 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.