Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 3/20 | 0.38 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013858 | 0.96 | — | — | |
| SCHEMBL9308476 | 0.96 | — | — | |
| SCHEMBL30774 | 0.96 | — | — | |
| Water SCHEMBL4908320 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL17242651 | 0.92 | — | — | |
| Formic Acid SCHEMBL3667112 | 0.86 | — | — | |
| Perchlorate SCHEMBL11635227 | 0.81 | GABRR1 (0.32) | GABRR1GABRR2BLMGABRR3LMNA | |
| Carbonotrithioic Acid SCHEMBL28273373 | 0.81 | CA1 (0.35) | GABRR1GABRR2BLMGABRR3LMNA | |
| Sulfurous Acid SCHEMBL11034327 | 0.81 | GABRR1 (0.38) | GABRR1GABRR2BLMGABRR3LMNA | |
| Bromide SCHEMBL28551347 | 0.81 | TSHR (0.45) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566903-A | By CO2Method for preparing carbonate by addition reaction with epoxide | 赢创运营有限公司 | 2021-03-26 | — | — | CN | disclosed |