Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.43 |
| ▸ | CCNK | O75909 | 5/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.43 |
| ▸ | CDK2 | P24941 | 5/20 | 0.43 |
| ▸ | CDK9 | P50750 | 5/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 5/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CCNH | P51946 | 1/20 | 0.42 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22895847 | 1.00 | IDH2 (0.54) | IDH2MAPK1CHEK1CCNT1CCNK | |
| Hydrochloric Acid SCHEMBL28544495 | 0.98 | IDH2 (0.53) | IDH2MAPK1CHEK1CCNT1CCNK | |
| Hydrochloric Acid SCHEMBL28544501 | 0.98 | IDH2 (0.53) | IDH2MAPK1CHEK1CCNT1CCNK | |
| Hydrochloric Acid SCHEMBL29777672 | 0.98 | IDH2 (0.53) | IDH2MAPK1CHEK1CCNT1CCNK | |
| SCHEMBL25222649 | 0.91 | IDH2 (0.56) | IDH2CHEK1CCNT1CCNKCCNE1 | |
| SCHEMBL28312479 | 0.91 | IDH2 (0.56) | IDH2CHEK1CCNT1CCNKCCNE1 | |
| SCHEMBL25258456 | 0.91 | IDH2 (0.56) | IDH2CHEK1CCNT1CCNKCCNE1 | |
| SCHEMBL31619971 | 0.90 | MAPK1 (0.56) | IDH2MAPK1CHEK1KCNH2 | |
| SCHEMBL26126794 | 0.87 | IDH2 (0.40) | IDH2MAPK1 | |
| SCHEMBL20576709 | 0.82 | CCNK (0.46) | IDH2MAPK1CHEK1CCNT1CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |