Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470878 | 0.85 | FOLH1 (0.63) | FOLH1GSK3BLMNAGLAPIN1 | |
| SCHEMBL23138998 | 0.83 | FOLH1 (0.60) | FOLH1GSK3BLMNAGLAPIN1 | |
| SCHEMBL7361177 | 0.83 | FOLH1 (0.60) | FOLH1GSK3BLMNAGLAPIN1 | |
| SCHEMBL20702757 | 0.83 | FOLH1 (0.60) | FOLH1GSK3BLMNAGLAPIN1 | |
| SCHEMBL29397955 | 0.81 | FOLH1 (0.59) | FOLH1DPP4DPP7FAPDPP8 | |
| SCHEMBL43812 | 0.81 | FOLH1 (0.59) | FOLH1DPP4DPP7FAPDPP8 | |
| SCHEMBL43811 | 0.81 | FOLH1 (0.59) | FOLH1DPP4DPP7FAPDPP8 | |
| SCHEMBL29557415 | 0.81 | FOLH1 (0.59) | FOLH1DPP4DPP7FAPDPP8 | |
| SCHEMBL12653044 | 0.81 | FOLH1 (0.59) | FOLH1LMNAGLAPIN1FFAR1 | |
| SCHEMBL838038 | 0.81 | FOLH1 (0.59) | FOLH1DPP4DPP7FAPDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563368-A | Boron-containing small molecules | 比尔及梅琳达盖茨基金会 | 2021-10-29 | — | — | CN | disclosed |
| CN-113321672-A | Boron-containing small molecules | 比尔及梅琳达盖茨基金会 | 2021-08-31 | — | — | CN | disclosed |
| CN-109195608-B | Boron-containing small molecules | 比尔及梅琳达盖茨基金会 | 2021-05-11 | — | — | CN | disclosed |