Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28550361 | 1.00 | GRIN2B (0.45) | GRIN2BGRIN2CACEJAK3MMP1 | |
| SCHEMBL28550363 | 1.00 | GRIN2B (0.45) | GRIN2BGRIN2CACEJAK3MMP1 | |
| SCHEMBL28545914 | 0.88 | GRIN2B (0.52) | GRIN2BGRIN2CJAK3 | |
| SCHEMBL28545915 | 0.88 | GRIN2B (0.52) | GRIN2BGRIN2CJAK3 | |
| SCHEMBL28545916 | 0.88 | GRIN2B (0.52) | GRIN2BGRIN2CJAK3 | |
| SCHEMBL23346959 | 0.85 | GRIN2B (0.56) | GRIN2BGRIN2CJAK3 | |
| SCHEMBL19229635 | 0.80 | GRIN2B (0.56) | GRIN2BGRIN2CJAK3 | |
| SCHEMBL18119907 | 0.80 | GRIN2B (0.56) | GRIN2BGRIN2CJAK3 | |
| SCHEMBL19229636 | 0.80 | GRIN2B (0.56) | GRIN2BGRIN2CJAK3 | |
| SCHEMBL24634170 | 0.80 | GRIN2B (0.47) | GRIN2BGRIN2CJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112745325-A | Pyrrole spiro-butyrolactam derivative and preparation thereof | 四川海思科制药有限公司 | 2021-05-04 | — | — | CN | disclosed |