Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.58 |
| ▸ | EGFR | P00533 | 5/20 | 0.57 |
| ▸ | CSF1R | P07333 | 6/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18087970 | 0.89 | HDAC1 (0.59) | HDAC1HDAC8HDAC6EGFRCSF1R | |
| SCHEMBL18088117 | 0.89 | HDAC1 (0.63) | HDAC1HDAC8HDAC6EGFRCSF1R | |
| SCHEMBL28550365 | 0.86 | EGFR (0.63) | HDAC1HDAC8HDAC6EGFRCSF1R | |
| SCHEMBL24653552 | 0.83 | EGFR (0.60) | HDAC1HDAC8HDAC6EGFRCSF1R | |
| SCHEMBL18087976 | 0.82 | HDAC1 (0.60) | HDAC1HDAC8HDAC6EGFRCSF1R | |
| SCHEMBL24653593 | 0.82 | EGFR (0.62) | HDAC1HDAC8HDAC6EGFRCSF1R | |
| SCHEMBL18088127 | 0.81 | HDAC1 (0.64) | HDAC1HDAC8HDAC6EGFRCSF1R | |
| SCHEMBL18088020 | 0.80 | HDAC1 (0.63) | HDAC1HDAC8HDAC6EGFRCSF1R | |
| SCHEMBL24653591 | 0.80 | EGFR (0.67) | HDAC1HDAC8HDAC6EGFRCSF1R | |
| SCHEMBL18088095 | 0.79 | HDAC1 (0.57) | HDAC1HDAC8HDAC6EGFRCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428705-B | Histone deacetylase inhibitor and preparation method and application thereof | 广东众生药业股份有限公司 | 2021-03-16 | — | — | CN | disclosed |