Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | FURIN | P09958 | 11/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29199017 | 0.89 | CKS1B (0.46) | CKS1BSKP1SKP2CNR1CNR2 | |
| SCHEMBL21564378 | 0.80 | FURIN (0.54) | CKS1BSKP1SKP2FURIN | |
| SCHEMBL21551220 | 0.80 | FURIN (0.47) | CKS1BSKP1SKP2FURINSUV39H2 | |
| SCHEMBL29891381 | 0.80 | FURIN (0.54) | CKS1BSKP1SKP2FURIN | |
| SCHEMBL28548809 | 0.78 | FURIN (0.48) | CKS1BSKP1SKP2FURINBTK | |
| SCHEMBL21550901 | 0.77 | FURIN (0.51) | CKS1BSKP1SKP2FURIN | |
| SCHEMBL28548808 | 0.77 | FURIN (0.51) | CKS1BSKP1SKP2FURIN | |
| SCHEMBL21551135 | 0.77 | FURIN (0.74) | FURIN | |
| SCHEMBL21550967 | 0.75 | FURIN (0.65) | FURIN | |
| SCHEMBL23339865 | 0.75 | CKS1B (0.54) | CKS1BSKP1SKP2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |