SCHEMBL28552172

SCHEMBL28552172

OC(/C=C/COCc1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.45
HTT P42858 2/20 0.44
CA1 P00915 3/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
ALOX5 P09917 1/20 0.43
TACR1 P25103 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.40
IDO1 P14902 1/20 0.38
RCE1 Q9Y256 1/20 0.38
MAPT P10636 1/20 0.38
TK1 P04183 1/20 0.37
AGXT P21549 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9007865 0.80 HTT (0.51) TSHRHTTCA1CA2CA7
SCHEMBL9586136 0.80 HTT (0.51) TSHRHTTCA1CA2CA7
SCHEMBL1524101 0.78 TSHR (0.67) TSHRHTTCA1CA2CA7
SCHEMBL1524098 0.78 TSHR (0.67) TSHRHTTCA1CA2CA7
SCHEMBL1524411 0.78 TSHR (0.67) TSHRHTTCA1CA2CA7
SCHEMBL9550253 0.78 CA1 (0.44) TSHRHTTCA1CA2CA7
SCHEMBL9739110 0.78 CA1 (0.44) TSHRHTTCA1CA2CA7
SCHEMBL9550255 0.78 CA1 (0.44) TSHRHTTCA1CA2CA7
SCHEMBL9739112 0.78 CA1 (0.44) TSHRHTTCA1CA2CA7
SCHEMBL24434511 0.77 TSHR (0.50) TSHRHTTCA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112675920-B Mono-chiral center catalyst, preparation thereof and method for catalytically synthesizing chiral alcohol compound and chiral alpha-allyl alcohol 南方科技大学 2022-12-20 CN disclosed
CN-112675920-A Mono-chiral center catalyst, preparation thereof and method for catalytically synthesizing chiral alcohol compound and chiral alpha-allyl alcohol 南方科技大学 2021-04-20 CN disclosed