Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 16/20 | 0.61 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.51 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13711655 | 0.96 | STAT3 (0.67) | STAT3LTB4R2 | |
| SCHEMBL2857060 | 0.93 | STAT3 (0.57) | STAT3LTB4R2 | |
| SCHEMBL2855361 | 0.91 | STAT3 (0.56) | STAT3LTB4R2 | |
| Meglumine SCHEMBL4454874 | 0.80 | STAT3 (0.46) | STAT3LTB4R2 | |
| SCHEMBL2861429 | 0.78 | STAT3 (0.63) | STAT3LTB4R2MEN1RECQLKMT2A | |
| SCHEMBL13711792 | 0.78 | STAT3 (0.67) | STAT3LTB4R2 | |
| SCHEMBL13711779 | 0.77 | STAT3 (0.58) | STAT3LTB4R2 | |
| SCHEMBL2470433 | 0.77 | STAT3 (0.59) | STAT3 | |
| SCHEMBL17077012 | 0.76 | STAT3 (1.00) | STAT3 | |
| SCHEMBL2472681 | 0.76 | STAT3 (0.64) | STAT3LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654247-B1 | ALKYNYL ARYL CARBOXAMIDES | MERCK SERONO SA (CH) | 2010-01-20 | — | — | EP | disclosed |