⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18541719 | 0.87 | — | — | |
| SCHEMBL1145639 | 0.87 | — | — | |
| SCHEMBL1145404 | 0.85 | — | — | |
| SCHEMBL3391138 | 0.77 | — | — | |
| SCHEMBL18163823 | 0.74 | — | — | |
| SCHEMBL10930481 | 0.73 | — | — | |
| SCHEMBL19905903 | 0.72 | — | — | |
| SCHEMBL25907132 | 0.71 | HRH3 (0.38) | — | |
| SCHEMBL23506373 | 0.69 | — | — | |
| SCHEMBL13741476 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112745307-A | Industrial preparation method of nifuratel | 南京乐锐斯医药科技有限公司 | 2021-05-04 | — | — | CN | claimed |
| CN-112724097-A | Preparation method of nifuratel intermediate | 南京乐锐斯医药科技有限公司 | 2021-04-30 | — | — | CN | claimed |
| CN-115541755-A | Quality control method of nifuratel tablets | 广东恒健制药有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-112745307-A | Industrial preparation method of nifuratel | 南京乐锐斯医药科技有限公司 | 2021-05-04 | — | — | CN | disclosed |
| CN-112745307-A | Industrial preparation method of nifuratel | 南京乐锐斯医药科技有限公司 | 2021-05-04 | — | — | CN | disclosed |
| CN-112724097-A | Preparation method of nifuratel intermediate | 南京乐锐斯医药科技有限公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-112724097-A | Preparation method of nifuratel intermediate | 南京乐锐斯医药科技有限公司 | 2021-04-30 | — | — | CN | disclosed |