Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.80 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.78 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13169536 | 0.98 | EPHX2 (0.83) | EPHX2EPHX1RAB9ATSHRNPC1 | |
| SCHEMBL3455859 | 0.98 | EPHX2 (0.83) | EPHX2EPHX1RAB9ATSHRNPC1 | |
| SCHEMBL17705940 | 0.97 | EPHX2 (0.75) | EPHX2EPHX1RAB9ATSHRNPC1 | |
| SCHEMBL4180735 | 0.93 | EPHX2 (0.69) | EPHX2EPHX1 | |
| SCHEMBL9260629 | 0.90 | EPHX2 (0.69) | EPHX2EPHX1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12932000 | 0.89 | EPHX2 (1.00) | EPHX2EPHX1RAB9ATSHRNPC1 | |
| SCHEMBL12196026 | 0.88 | EPHX1 (1.00) | EPHX2EPHX1RAB9ATSHRNPC1 | |
| SCHEMBL6700011 | 0.87 | EPHX2 (0.62) | EPHX2EPHX1HPGD | |
| SCHEMBL4022912 | 0.87 | EPHX2 (0.62) | EPHX2EPHX1HPGD | |
| SCHEMBL22301532 | 0.86 | EPHX1 (0.97) | EPHX2EPHX1RAB9ATSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110066254-B | Preparation method of isothiazole-3-ketone compound | 温州大学 | 2021-03-19 | — | — | CN | disclosed |