Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | CDC25B | P30305 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38652447 | 0.82 | POLB (0.84) | KDM4ELMNAPOLBBCL2L1GLA | |
| SCHEMBL5543562 | 0.82 | POLB (0.84) | KDM4ELMNAPOLBBCL2L1GLA | |
| SCHEMBL28559166 | 0.81 | KDM4E (0.69) | KDM4ELMNAPOLBBCL2L1GLA | |
| SCHEMBL24704031 | 0.80 | KDM4E (1.00) | KDM4ELMNAPOLBBCL2L1GLA | |
| SCHEMBL28554342 | 0.80 | KDM4E (0.76) | KDM4ELMNAPOLBBCL2L1GLA | |
| SCHEMBL28574496 | 0.80 | KDM4E (0.71) | KDM4ELMNAPOLBBCL2L1GLA | |
| SCHEMBL28559246 | 0.79 | KDM4E (0.67) | KDM4ELMNAPOLBBCL2L1GLA | |
| SCHEMBL28563327 | 0.78 | POLB (0.78) | KDM4ELMNAPOLBBCL2L1GLA | |
| SCHEMBL28564823 | 0.77 | KDM4E (0.65) | KDM4ELMNAPOLBBCL2L1GLA | |
| SCHEMBL28563150 | 0.77 | POLB (0.80) | KDM4ELMNAPOLBBCL2L1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638909-A | Compounds with antibacterial activity | 香港理工大学 | 2021-04-09 | — | — | CN | disclosed |