Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 20/20 | 0.80 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.58 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.58 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28550464 | 0.89 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL28553952 | 0.87 | FGFR4 (0.75) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL28561621 | 0.84 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL28557981 | 0.83 | FGFR4 (0.85) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL20094039 | 0.81 | FGFR4 (0.85) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL20094037 | 0.81 | FGFR4 (0.85) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL20094405 | 0.81 | FGFR4 (0.85) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL20094042 | 0.81 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL28550461 | 0.80 | FGFR4 (0.84) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL28559774 | 0.79 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108503593-B | 2-aminopyrimidine compounds and application thereof | 暨南大学 | 2021-04-27 | — | — | CN | claimed |
| CN-108503593-B | 2-aminopyrimidine compounds and application thereof | 暨南大学 | 2021-04-27 | — | — | CN | disclosed |