Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28558196

Cc1cc(S(=O)(=O)Nc2cscn2)ncc1N(C)[C@H]1CCN(Cc2cc(F)ccc2F)C1.O=C(O)C(F)(F)F

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 20/20 0.89
SCN8A Q9UQD0 20/20 0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL21773215 0.97 SCN1A (0.83) SCN1ASCN8A
SCHEMBL21773044 0.94 SCN1A (1.00) SCN1ASCN8A
SCHEMBL21773047 0.94 SCN1A (1.00) SCN1ASCN8A
Trifluoroacetic Acid SCHEMBL19613730 0.90 SCN8A (0.89) SCN1ASCN8A
Trifluoroacetic Acid SCHEMBL19613729 0.90 SCN8A (0.89) SCN1ASCN8A
Trifluoroacetic Acid SCHEMBL30845663 0.89 SCN8A (0.89) SCN1ASCN8A
Trifluoroacetic Acid SCHEMBL19613268 0.87 SCN8A (0.89) SCN1ASCN8A
Trifluoroacetic Acid SCHEMBL19613267 0.87 SCN8A (0.89) SCN1ASCN8A
SCHEMBL21773150 0.86 SCN8A (1.00) SCN1ASCN8A
SCHEMBL21773146 0.86 SCN8A (1.00) SCN1ASCN8A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638898-B Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors 泽农医药公司 2024-04-09 CN disclosed
CN-112638898-A Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors 泽农医药公司 2021-04-09 CN disclosed