Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK12 | Q9NYV4 | 19/20 | 0.54 |
| ▸ | CCNK | O75909 | 18/20 | 0.54 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28559075 | 1.00 | CDK12 (0.54) | CDK12CCNKCDK13USP30 | |
| SCHEMBL23292315 | 1.00 | CDK12 (0.54) | CDK12CCNKCDK13USP30 | |
| SCHEMBL23292344 | 0.93 | CCNK (0.61) | CDK12CCNKCDK13 | |
| SCHEMBL22895516 | 0.93 | CCNK (0.61) | CDK12CCNKCDK13 | |
| SCHEMBL23325385 | 0.93 | CCNK (0.61) | CDK12CCNKCDK13 | |
| SCHEMBL31548536 | 0.93 | CCNK (0.61) | CDK12CCNKCDK13 | |
| SCHEMBL23292317 | 0.91 | CCNK (0.45) | CDK12CCNKCDK13USP30 | |
| SCHEMBL23292276 | 0.87 | CCNK (0.57) | CDK12CCNKCDK13 | |
| SCHEMBL23292283 | 0.87 | CDK12 (0.55) | CDK12CCNKCDK13USP30 | |
| SCHEMBL22895937 | 0.87 | CCNK (0.57) | CDK12CCNKCDK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |